PreprintALSYEATSChemical probe
A leukemia-derived ENL/AF9 chemical probe enhances neuronal stress resilience and ameliorates ALS phenotypes
Lo Piccolo, L., P., C., Yeewa, R., Yubolphan, R., Potikanond, S., Jantrapirom, S.
bioRxiv (preprint), 2026
Paper & Preprint
A selection of relevant work.
Selected papers and preprints from our team, spanning leading journals in molecular biology, genetics, and neurological diseases.
2026
4 papersNeurotoxicologyDrosophilaAging
Diesel exhaust particles induce lasting and age-dependent damage to the brain in Drosophila melanogaster
Yeewa, R., et al.
Neurotoxicology, 2026
YEATS2DopaminergicCalcium
Dopaminergic neurons are vulnerable to dysregulation of YEATS2-dependent calcium homeostasis
Lo Piccolo, L., et al.
iScience, 2026
ER stressDrug discoveryAging
Discovery of a pyrazolopyridine alkaloid that mitigates neuronal ER stress and age-related decline
Jantrapirom, S., et al.
Communications Biology, 2026
2024
3 papersERO1AALSUBQLN2
ERO1A inhibition mitigates neuronal ER stress and ameliorates UBQLN2(ALS) phenotypes in Drosophila melanogaster
Yeewa, R., et al.
Progress in Neurobiology, 2024
ENL/AF9AgingHistone acylation
The histone acylation reader ENL/AF9 regulates aging in Drosophila melanogaster
Yeewa, R., et al.
Neurobiology of Aging, 2024
FAME4YEATS2Seizures
FAME4-associating YEATS2 knockdown impairs dopaminergic synaptic integrity and leads to seizure-like behaviours in Drosophila melanogaster
Lo Piccolo, L., et al.
Progress in Neurobiology, 2024
2023
1 paperDrug repurposingFingolimodTDP-43
A Novel Drosophila-based Drug Repurposing Platform Identified Fingolimod As a Potential Therapeutic for TDP-43 Proteinopathy
Lo Piccolo, L., et al.
Neurotherapeutics, 2023
2022
1 paperReviewYEATSNeurological diseases
Multifaceted roles of YEATS domain-containing proteins and novel links to neurological diseases
Yeewa, R., Chaiya, P., Jantrapirom, S., Shotelersuk, V., Lo Piccolo, L.
Cellular and Molecular Life Sciences, 2022
2021
1 paperlncRNAMethylationReview
Long noncoding RNA-dependent methylation of nonhistone proteins
Jantrapirom, S., et al.
Wiley Interdisciplinary Reviews: RNA, 2021